VDJdb is a curated database of T-cell receptor (TCR) sequences with known antigen specificities. The primary goal of VDJdb is to facilitate access to existing information on T-cell receptor antigen specificities, i.e. the ability to recognize certain epitopes in a certain MHC contexts.
Our mission is to both aggregate the scarce TCR specificity information available so far and to create a curated repository to store such data. In addition to routine database updates providing the most up-to-date information fetched from recently published studies utilizing TCR specificity assays, we make our best to ensure data consistency and correct irregularities in TCR specificity reporting with a complex database validation scheme:
The web application you are viewing right now can be used to browse and query the database, providing an intuitive interface for database navigation. Additionally, it can be used to query immune repertoire sequencing (RepSeq) samples against the database and generate sample-level summary of detected antigen specificities.
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For more information on VDJdb and downstream analysis tools please visit the About section